|
Cardiologist
in the United States
1.3% are active smokers,
89% exercise regularly,
72% drink red wine at
least once a week.
4% have coronary
problems,
28% have dyslipidemia,
14% are hypertensive,
0.6% are diabetics.
These statistics show much better lifestyle among Cardiologists
than general population and even compared with other physicians.
Source
= Am J Cardiol 2006;97:1093-1096
|
|
Early
agressive statin therapy : pretty
simple to save lives
Less mortality, reinfarction, and
revascularization need
when Statins are initiated during
the acute
phase of an ischemic event.
follow-up :15 months
aggressive statin
therapy : 25% risk reduction.
Source
= ACC 55th Annual Scientific
Session March 13, 2006 Abstract 821-5
|
|
Sleep duration
Sleep duration between 6
and 8 hours at night has a U-shaped distribution of risk concerning diabetes
in men: risk of diabetes increase by 2 % for less than 6 hours sleep
duration and by 3 for those men who sleep more than 8 hours.
Reminder: this sleep
duration risk has been reported previously for coronary heart disease,
diabetes in women and all cause mortality.
Source
= Diabetes Care 2006;29:657-661
|
|
Methotrexate and chronic heart failure
Inflammatory mediators TNF-alpha,
MCP-1, sICAM-1, and CRP reduction by early low dose administration of
methotrexate for twelve weeks improve
symptoms and quality-of-life in chronic heart failure patients.
Improvement occurs for NYHA functional class, 6-minute walk
test distance, and quality-of-life scores.
Source
= Am Heart J 2006;151:62-68
|
Survival
in chronic heart failure.
Beta
blockers increase fat mass which seems to significantly improve survival in
CHF patients.
Source = Int J Cardiol 2006;106:319-322
|
|
Less severe infection
with statins
Statins
have
lipid-lowering
anti-inflammatory
antioxidant
properties
endothelial
function improvement
cellular
immunity modulation
all that may contribute
to Reduced Sepsis Risk by 19 %.
Source
= the January 25th online issue of The Lancet
|
|
Cardiovascular
events are linked to composition, morphology, and stability of plaque more
than the amount of atherosclerotic plaque.
|
Statins'
anti-inflammatory and plaque-stabilising properties reduce stroke incidence.
|
|
High LDL cholesterol and
mortality risk:
In younger patients,
High LDL, high mortality
In elderly patients,
High LDL, lower mortality
Caution about LDL value
interpretation is required.
Source
= J Am Geriatr Soc 2005;53:2159-2164
|
|
The
'goal LDL' concept is outdated.
Patients with an LDL
cholesterol level of 80 mg/dL or lower are at 29.0% risk of death,
reinfarction, or stroke at six months.
Same patients who were
discharged on statin therapy have
9.5% risk of death, reinfarction, or stroke at six months.
Source
: Am J Cardiol 2005;96:1491-1493
|
|
The
identification of patients at risk for acute plaque rupture events may be
possible in the near future by reagents under development to detect
overexpression of activated MMP-9.
Source
= J Clin Invest 2005
|
Alzheimer's disease
patients have othostatic hypotension, low Heart rate variability time
because of autonomic cardiovascular dysfunction.
Source
= J Am Geriatr Soc 2005;53:2135-2139
|
|
Although Blood Pressure and cardiovascular
mortality are lower in hot months and higher in cold months, Blood Pressure is higher in the elderly
during hot weather nights.
Source
= Hypertension 2005;47
|
|
Prevention of
chemotherapy chronic cardiotoxicity can be obtained by ARB.
Source
= Cancer 2005;104:2492-2498
|
HSP60
and early carotid atherosclerosis
sHSP60 and chronic infection increase
the risk of early atherogenesis.
Source = Stroke 2005;36:2571-2576
|
|
Low meat and
high vegetable intakes prevent the development of elevated blood pressure.
Dairy consumption does
not have a consistent effect on blood pressure
Source
= Am J Clin Nutr 2005;82:1169-1177
|
